Structure of PDB 6b9l Chain A Binding Site BS02
Receptor Information
>6b9l Chain A (length=174) Species:
9606
(Homo sapiens) [
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KEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDMPIYMYSVCNVMSGD
QDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAES
DLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRK
GFYLAFQDIGACVALLSVRVYYKK
Ligand information
>6b9l Chain G (length=10) Species:
32644
(unidentified) [
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SAYPDSVPFR
Receptor-Ligand Complex Structure
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PDB
6b9l
Structure-Based Design of Novel EphA2 Agonistic Agents with Nanomolar Affinity in Vitro and in Cell.
Resolution
3.2 Å
Binding residue
(original residue number in PDB)
V72 M73
Binding residue
(residue number reindexed from 1)
V46 M47
Enzymatic activity
Enzyme Commision number
2.7.10.1
: receptor protein-tyrosine kinase.
External links
PDB
RCSB:6b9l
,
PDBe:6b9l
,
PDBj:6b9l
PDBsum
6b9l
PubMed
30110533
UniProt
P29317
|EPHA2_HUMAN Ephrin type-A receptor 2 (Gene Name=EPHA2)
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