Structure of PDB 6b1r Chain A Binding Site BS02

Receptor Information

>6b1r Chain A (length=242) Species: 11801 (Moloney murine leukemia virus)

TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLG
IKPHIQRLLDQGILVPCQSPWNTPLLPVYRPVQDLREVNKRVEDIHPTVP
NPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRSGQLTWT
RLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAATSELDC
QQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR

Ligand information

>6b1r Chain G (length=8)

aaaataag

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6b1r Skinny" and "Fat" DNA: Two New Double Helices.
• Resolution: 1.69 Å
• Binding residue (original residue number in PDB): L99 D114 L115 R116
• Binding residue (residue number reindexed from 1): L76 D84 L85 R86

Enzymatic activity

• Enzyme Commision number: 2.7.7.-
  2.7.7.49: RNA-directed DNA polymerase.
  2.7.7.7: DNA-directed DNA polymerase.
  3.1.-.-
  3.1.26.4: ribonuclease H.
  3.4.23.-

External links

• PDB: RCSB:6b1r, PDBe:6b1r, PDBj:6b1r
• PDBsum: 6b1r
• PubMed: 30148365
• UniProt: P03355|POL_MLVMS Gag-Pol polyprotein (Gene Name=gag-pol)