Structure of PDB 6agi Chain A Binding Site BS02

Receptor Information
>6agi Chain A (length=303) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEPKVTWKSLSKQELNQ
MLAETPPVWKGSSKLFRNLKEKGVISYTEYLFLLCILTKPHAGFRIAFNM
FDTDGNEMVDKKEFLVLQEIFRDEEKRAMLRLQLYGVTDTTLLVHFFGKK
GKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTN
VENTSVFLENVRYSIPEEKGITFDEFRSFFQFLNNLEDFAIALNMYNFAS
RSIGQDEFKRAVYVATGLKFSPHLVNTVFKIFDVDKDDQLSYKEFIGIMK
DRL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6agi Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6agi Dimerization of MICU Proteins Controls Ca2+Influx through the Mitochondrial Ca2+Uniporter.
Resolution2.799 Å
Binding residue
(original residue number in PDB)		D483 D485 D487 Q489 E494
Binding residue
(residue number reindexed from 1)		D283 D285 D287 Q289 E294
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0006851 mitochondrial calcium ion transmembrane transport

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Molecular Function
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Biological Process
External links
PDB RCSB:6agi, PDBe:6agi, PDBj:6agi
PDBsum6agi
PubMed30699349
UniProtQ86XE3|MICU3_HUMAN Calcium uptake protein 3, mitochondrial (Gene Name=MICU3)

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