Structure of PDB 6a6m Chain A Binding Site BS02

Receptor Information
>6a6m Chain A (length=589) Species: 280699 (Cyanidioschyzon merolae strain 10D) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTGVTARRIFALAWSSSATMIVIGFIASILEGATLPAFAIVFGRMFAVFT
KSKSQIEGETWKYSVGFVGIGVFEFIVAGSRTALFGIASERLARDLRVAA
FSNLVEQDVTYFDRRKAGELGGKLNNDVQVIQYSFSKLGAVLFNLAQCVV
GIIVAFIFAPALTGVLIALSPLVVLAGAAQMIEMSGNTKRSSEAYASAGS
VAAEVFSNIRTTKAFEAERYETQRYGSKLDPLYRLGRRRYISDGLFFGLS
MLVIFCVYALALWWGGQLIARGSLNLGNLLAAFFSAILGFMGVGQAAQVW
PDVTRGLGAGGELFAMIDRVPQYRRPDPGAEVVTQPLVLKQGIVFENVHF
RYPTRMNVEVLRGISLTIPNGKTVAIVGGSGAGKSTIIQLLMRFYDIEPQ
GGGLLLFDGTPAWNYDFHALRSQIGLVSQEPVLFSGTIRDNILYGKRDAT
DEEVIQALREANAYSFVMALPDGLDTEVGERGLALSGGQKQRIAIARAIL
KHPTLLCLDESTSALDAESEALVQEALDRMMASDGVTSVVIAHRLSTVAR
ADLILVMQDGVVVEQGNHSELMALGPSGFYYQLVEKQLA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6a6m Chain A Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6a6m Inward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB1.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		S485 Q529
Binding residue
(residue number reindexed from 1)		S385 Q429
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6a6m, PDBe:6a6m, PDBj:6a6m
PDBsum6a6m
PubMed30622258
UniProtM1VAN7

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