Structure of PDB 6a1z Chain A Binding Site BS02

Receptor Information
>6a1z Chain A (length=352) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKVKVAVRVRPMNRREIDLHTKCVVDVEANKVILNPINQPKIFAYDHCFW
SMDESVREKYAGQDDVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTM
MGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLD
PKGSRQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVASS
RSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSENINKSLTTLGLV
ISALADQGAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADN
YDETLSTLRYADRAKHIINHAVVNEDPNARIIRDLREEVEKLREQLTKAE
AM
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6a1z Chain A Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6a1z Coiled-coil 1-mediated fastening of the neck and motor domains for kinesin-3 autoinhibition.
Resolution2.58 Å
Binding residue
(original residue number in PDB)		Q104 T329 V330 T343
Binding residue
(residue number reindexed from 1)		Q91 T293 V294 T307
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:6a1z, PDBe:6a1z, PDBj:6a1z
PDBsum6a1z
PubMed30463954
UniProtA0A0G2K8Z9

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