Structure of PDB 5zyv Chain A Binding Site BS02

Receptor Information
>5zyv Chain A (length=197) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VIPSVTRVLQQTMTKQQVFLLERWKQRMILELGEDGFKEYTSNVFLQGKR
FQEALESILSDENLLKSGYIESVQHILKDVSGVRALESAVQHETLNYIGL
LDCVAEYQGKLCVIDWKTSEKPKPFIQSTFDNPLQVVAYMGAMNHDTNYS
FQVQCGLIVVAYKDGSPAHPHFMDAELCSQYWTKWLLRLEEYTEKKK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5zyv Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5zyv Structural insights into DNA degradation by human mitochondrial nuclease MGME1
Resolution2.72 Å
Binding residue
(original residue number in PDB)		D238 D251 W252
Binding residue
(residue number reindexed from 1)		D102 D115 W116
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
External links
PDB RCSB:5zyv, PDBe:5zyv, PDBj:5zyv
PDBsum5zyv
PubMed30247721
UniProtQ9BQP7|MGME1_HUMAN Mitochondrial genome maintenance exonuclease 1 (Gene Name=MGME1)

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