Structure of PDB 5zs6 Chain A Binding Site BS02

Receptor Information
>5zs6 Chain A (length=112) Species: 216594 (Mycobacterium marinum M) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LGTSARPAVMPMDAWREGDKFVVEFDLPGIDADSLDIDIERNVVTVRAER
PAVDPNREMLASERPRGVFSRQLVLGENLDTARIAASYTEGVLKLQIPVA
EKAKPRKISITR
Ligand information
Ligand IDPRO
InChIInChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1
InChIKeyONIBWKKTOPOVIA-BYPYZUCNSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C1C[C@H](NC1)C(=O)O
CACTVS 3.341OC(=O)[C@@H]1CCCN1
CACTVS 3.341OC(=O)[CH]1CCCN1
OpenEye OEToolkits 1.5.0C1CC(NC1)C(=O)O
ACDLabs 10.04O=C(O)C1NCCC1
FormulaC5 H9 N O2
NamePROLINE
ChEMBLCHEMBL54922
DrugBankDB00172
ZINCZINC000000895360
PDB chain5zs6 Chain A Residue 204 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5zs6 Dodecameric structure of a small heat shock protein from Mycobacterium marinum M.
Resolution2.81191 Å
Binding residue
(original residue number in PDB)		R124 K125
Binding residue
(residue number reindexed from 1)		R106 K107
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0051082 unfolded protein binding
Biological Process
GO:0006457 protein folding
GO:0009408 response to heat
GO:0009651 response to salt stress
GO:0042542 response to hydrogen peroxide
GO:0051259 protein complex oligomerization

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Molecular Function
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Biological Process
External links
PDB RCSB:5zs6, PDBe:5zs6, PDBj:5zs6
PDBsum5zs6
PubMed30632633
UniProtB2HF11

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