Structure of PDB 5zm4 Chain A Binding Site BS02

Receptor Information
>5zm4 Chain A (length=285) Species: 1549217 (Aspergillus stellatus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMPPIRRVNASQGSDAAYQILQEDGCVIVEQVICPNIIAKISDDVNRVMD
KATIGAKKGEQTHIINMHNRTIHMGDLVLTSKTYRDELLNLPFAHEVLEK
VFKKDSGDYWLNMGNILNMLPGAEAQRPHRDDYLYPVSQHMDPATSPDLM
INITFPLNEFRHDNGGTLLLPKSHTGPNADFYANAEDLPAAEMQVGDALI
FTGKCVHGGGANRSDKPRIGLALAAQPGYLTPRESNVNVPRDIVETMTPL
AQRMIGWGTVRTKDTYGLNMLQDKDFHEALGLKSK
Ligand information
Ligand IDAKG
InChIInChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChIKeyKPGXRSRHYNQIFN-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(O)C(=O)CCC(=O)O
OpenEye OEToolkits 1.7.6C(CC(=O)O)C(=O)C(=O)O
CACTVS 3.385OC(=O)CCC(=O)C(O)=O
FormulaC5 H6 O5
Name2-OXOGLUTARIC ACID
ChEMBLCHEMBL1686
DrugBankDB08845
ZINCZINC000001532519
PDB chain5zm4 Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5zm4 Structural and Computational Bases for Dramatic Skeletal Rearrangement in Anditomin Biosynthesis.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		Q132 H135 T173 H213 G215 R224
Binding residue
(residue number reindexed from 1)		Q126 H129 T167 H207 G209 R218
Annotation score4
Enzymatic activity
Enzyme Commision number 1.14.11.-
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0016114 terpenoid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5zm4, PDBe:5zm4, PDBj:5zm4
PDBsum5zm4
PubMed29972643
UniProtA0A097ZPD5|ANDA_EMEVA Dioxygenase andA (Gene Name=andA)

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