Structure of PDB 5zdk Chain A Binding Site BS02

Receptor Information
>5zdk Chain A (length=543) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGLVPECFITELVERDLKEGKYAKLVTRFPPEPNGYLHIGHARSIVLNFG
LAQDYGGECNLRFDDTNPETEKEEYARAIEEDVRWLGFRPTRVLYASDYF
ETMYQCALVLIQEGKAYVDDLPEEEMSELRAQGKPSPYRERSVEENLELF
ERMRRGEFPTGSRVLRAKIDPAHPNFKLRDPVLYRIVHAPHYHVGDRWVI
YPMYDFAHPLEDFIEGVTHSLCTLEFENNRTVYDWVIENLKGKCGLPTSP
RPHQYEFARLDLSHTVLSKRKLIKLVEGGYVSGWDDPRLPTLRGLRRRGV
RPEAIVEFVRKTGISRNEAQIEMDLFEEVVRDDLNPIAPRVLGVVDPLKV
VLTNYEGEEWIEAPYWPRDIPKEGTRPLPFSPELYIERTDFSLNPPKGWK
RLAPGQRVRLRHAYVIELEDVVEEGGEVRLLKARIVPGTLGANPEDGVRP
KGVIHWVSARHALPVEFRLYGRLFRTKDPEEGGDFLQNLNPEALVVKRGF
IEPSVAQDPEDTRYQLERLGYFWRDPVDSRPEALVMNRIVPLK
Ligand information
Ligand IDCS
InChIInChI=1S/Cs/q+1
InChIKeyNCMHKCKGHRPLCM-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Cs+]
FormulaCs
NameCESIUM ION
ChEMBL
DrugBank
ZINC
PDB chain5zdk Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5zdk Structural and functional analysis of Glutaminyl-tRNA synthetase (TtGlnRS) from Thermus thermophilus HB8 and its complexes
Resolution2.45 Å
Binding residue
(original residue number in PDB)		W366 P367 I370 E373
Binding residue
(residue number reindexed from 1)		W366 P367 I370 E373
Annotation score1
Enzymatic activity
Enzyme Commision number 6.1.1.18: glutamine--tRNA ligase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004819 glutamine-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006425 glutaminyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5zdk, PDBe:5zdk, PDBj:5zdk
PDBsum5zdk
PubMed30248426
UniProtQ5SKU4

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