Structure of PDB 5z8l Chain A Binding Site BS02

Receptor Information
>5z8l Chain A (length=204) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAKTRPGVASKIKTGRKELDSYTIKGTNKVVRAGDCVLMRPSDAGKPPYV
ARVEKIEADANVKVHCRWYYRPEESLGGRRQFHGAKELFLSDHFDVQSAH
TIEGKCIVHTFKNYTRLENVGAEDYYCRFEYKAATGAFTPDRVAVYCKCE
MPYNPDDLMVQCEGCKDWYHPACVGMTIEEAKKLDHFVCAECSSPADDVK
VRLS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5z8l Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5z8l EBS is a bivalent histone reader that regulates floral phase transition in Arabidopsis.
Resolution2.005 Å
Binding residue
(original residue number in PDB)		C149 C151 H172 C175
Binding residue
(residue number reindexed from 1)		C147 C149 H170 C173
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0035064 methylated histone binding
GO:0046872 metal ion binding
GO:0140678 molecular function inhibitor activity
Biological Process
GO:0006325 chromatin organization
GO:0009791 post-embryonic development
GO:0009845 seed germination
GO:0009908 flower development
GO:0045814 negative regulation of gene expression, epigenetic
GO:0048579 negative regulation of long-day photoperiodism, flowering
GO:2000028 regulation of photoperiodism, flowering
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5z8l, PDBe:5z8l, PDBj:5z8l
PDBsum5z8l
PubMed30082787
UniProtF4JL28|EBS_ARATH Chromatin remodeling protein EBS (Gene Name=EBS)

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