Structure of PDB 5z0k Chain A Binding Site BS02

Receptor Information
>5z0k Chain A (length=276) Species: 79261 (Streptomyces castaneoglobisporus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TVRKNQATLTADEKRRFVAAVLELKRSGRYDEFVRTHNEFIMSDTDSGER
TGHRSPSFLPWHRRFLLDFEQALQSVDSSVTLPYWDWSADRTVRASLWAP
DFLGGTGRSTDGRVMDGPFAASTGNWPINVRVDSRTYLRRSLGGSVAELP
TRAEVESVLAISAYDLPPYNSASEGFRNHLEGWRGVNLHNRVHVWVGGQM
ATGVSPNDPVFWLHHAYVDKLWAEWQRRHPDSAYVPTGGTPDVVDLNETM
KPWNTVRPADLLDHTAYYTFDALEHH
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain5z0k Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5z0k Catalytic mechanism of tyrosinase implied from the quinone formation on the Tyr98 residue of the caddie protein
Resolution1.28 Å
Binding residue
(original residue number in PDB)		H190 H194 H216
Binding residue
(residue number reindexed from 1)		H189 H193 H215
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.18.1: tyrosinase.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5z0k, PDBe:5z0k, PDBj:5z0k
PDBsum5z0k
PubMed
UniProtQ83WS2

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