Structure of PDB 5yz9 Chain A Binding Site BS02

Receptor Information
>5yz9 Chain A (length=99) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFRRIINKHTD
ESLGDCSFLNTCFHMDTCKYVHYEIDASMDSEAPGSKDHTPSQELALTQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5yz9 Chain A Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5yz9 Solution structure of the RNA recognition domain of METTL3-METTL14 N6-methyladenosine methyltransferase.
ResolutionN/A
Binding residue
(original residue number in PDB)		C314 C326 H330
Binding residue
(residue number reindexed from 1)		C56 C68 H72
Annotation score1
Enzymatic activity
Enzyme Commision number 2.1.1.348: mRNA m(6)A methyltransferase.
External links
PDB RCSB:5yz9, PDBe:5yz9, PDBj:5yz9
PDBsum5yz9
PubMed29542011
UniProtQ86U44|MTA70_HUMAN N6-adenosine-methyltransferase catalytic subunit (Gene Name=METTL3)

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