Structure of PDB 5ykn Chain A Binding Site BS02

Receptor Information
>5ykn Chain A (length=478) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RWNPSEACRPLVDDAPIFYPTNEDFDDPLGYIEKLRSKAESYGICRIVPP
VAWRPPCPLKEKKIWENSKFPTRIQFIDLLQNRFGFQTGPDFTLAAFQKY
DEYFKECYFQPKVKDLEGEYWRIVEQATDEVEVYYGADLETKKFGSGFPK
YKPGYPISEADQYSQCGWNLNNLSRLPGSVLAFESCDISGVIVPWLYVGM
CFSTFCWHVEDHHLYSMNYLHTGDPKVWYGIPGNHAESFENVMKKRLPDL
FEEQPDLLHQLVTQLSPRILKEEGVPVYRAVQRSGEFILTFPKAYHSGFN
CGFNCAEAVNVAPVDWLVHGQNAVEGYSKQRRKSSLSHDKLLLGAAMEAT
YCLWELSLSKKKTPVIARWKRVCSEDGLLTKAVKKRVQMEEERLNHLQDG
FSLRKMRECFLCFYDLHMSASSCKCSPNRFACLIHAKDLCSCESKDRYIL
IRHTLDELWALVRALEGDLDAIDLWASK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5ykn Chain A Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ykn Structure of the Arabidopsis JMJ14-H3K4me3 Complex Provides Insight into the Substrate Specificity of KDM5 Subfamily Histone Demethylases.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		C533 C535 C550 C552
Binding residue
(residue number reindexed from 1)		C423 C425 C440 C442
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.11.67: [histone H3]-trimethyl-L-lysine(4) demethylase.
External links
PDB RCSB:5ykn, PDBe:5ykn, PDBj:5ykn
PDBsum5ykn
PubMed29233856
UniProtQ8GUI6|JMJ14_ARATH Lysine-specific demethylase JMJ14 (Gene Name=JMJ14)

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