Structure of PDB 5yf4 Chain A Binding Site BS02

Receptor Information
>5yf4 Chain A (length=129) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCAAHKTP
KECPAIDYTRHTLDGAACLLNSAKLGSVCRRIYRIFSHAYFHHRQIFDEY
ENETFLCHRFTKFVMKYNLMSKDNLIVPI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5yf4 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5yf4 The MST4-MOB4 complex disrupts the MST1-MOB1 complex in the Hippo-YAP pathway and plays a pro-oncogenic role in pancreatic cancer.
Resolution1.897 Å
Binding residue
(original residue number in PDB)		C110 H113 C119 H127
Binding residue
(residue number reindexed from 1)		C44 H47 C53 H61
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5yf4, PDBe:5yf4, PDBj:5yf4
PDBsum5yf4
PubMed30072378
UniProtQ9Y3A3|PHOCN_HUMAN MOB-like protein phocein (Gene Name=MOB4)

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