Structure of PDB 5y5p Chain A Binding Site BS02

Receptor Information
>5y5p Chain A (length=170) Species: 654913 (Shrimp white spot syndrome virus (isolate Tongan)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DSSASVVFMRFAPPGEETALPPRRATPGSVAYDLFPSEEMDIEPMGLAKI
STGYGIDKFPDGCYGQIVSRSGMTWKNNTSVPTGTIDVDYRGELKVILRN
HSAEKSVPIRKGTSIAQLIFLRYCDVEEEQIVYINETTGERTIIDSSSKK
DNKNQARSVRGTGGFGSTDN
Ligand information
Ligand IDPOP
InChIInChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-2
InChIKeyXPPKVPWEQAFLFU-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0O[P@@](=O)([O-])O[P@@](=O)(O)[O-]
CACTVS 3.341O[P]([O-])(=O)O[P](O)([O-])=O
ACDLabs 10.04[O-]P(=O)(O)OP([O-])(=O)O
OpenEye OEToolkits 1.5.0OP(=O)([O-])OP(=O)(O)[O-]
FormulaH2 O7 P2
NamePYROPHOSPHATE 2-
ChEMBL
DrugBank
ZINC
PDB chain5y5p Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5y5p The dUTPase of white spot syndrome virus assembles its active sites in a noncanonical manner.
Resolution2.03 Å
Binding residue
(original residue number in PDB)		R161 G165 G167 S168 T169
Binding residue
(residue number reindexed from 1)		R160 G164 G166 S167 T168
Annotation score5
Enzymatic activity
Enzyme Commision number 3.6.1.23: dUTP diphosphatase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004170 dUTP diphosphatase activity
Biological Process
GO:0006226 dUMP biosynthetic process
GO:0046081 dUTP catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5y5p, PDBe:5y5p, PDBj:5y5p
PDBsum5y5p
PubMed29187596
UniProtQ77J78

[Back to BioLiP]