Structure of PDB 5y3m Chain A Binding Site BS02

Receptor Information
>5y3m Chain A (length=738) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPAFLPCELQPHGQVDCNWLFLKSVPHFSAGAPRANVTSLSLISNRIHHL
HDSDFVHLSNLRVLNLKWNCPPAGLSPMHFPCRMTIEPNTFLAVPTLEEL
NLSYNGITTVPALPSSLVSLSLSHTSILVLGPTHFTGLHALRFLYMDGNC
YYMNPCPRALEVAPGALLGLGNLTHLSLKYNNLTEVPRRLPPSLDTLLLS
YNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCRECPKNFPKLHPD
TFSHLSRLEGLVLKDSSLYKLEKDWFRGLGRLQVLDLSENFLYDYITKTT
IFNDLTQLRRLNLSFNYHKKVSFAHLHLASSFGSLVSLEKLDMHGIFFRS
LTNITLQSLTRLPKLQSLHLQLNFINQAQLSIFGAFPSLLFVDLSDNRIS
GAMPSCNLNFTLDLSRNNLVTIQQEMFTRLSRLQCLRLSHNSISQAVNGS
QFVPLTSLRVLDLSHNKLDLYHGRSFTELPQLEALDLSYNSQPFSMQGVG
HNLSFVAQLPSLRYLSLAHNGIHSRVSQKLSSASLRALDFSGNSLSQMWA
EGDLYLCFFKGLRNLVQLDLSENHLHTLLPRHLDNLPKSLRQLRLRDNNL
AFFNWSSLTVLPRLEALDLAGNQLKALSNGSLPPGIRLQKLDVSSNSIGF
VIPGFFVRATRLIELNLSANALKTVDPSWFGSLAGTLKILDVSANPLHCA
CGAAFVDFLLERQEAVPGLSRRVTCGSPGQLQGRSIFT
Ligand information
Receptor-Ligand Complex Structure
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PDB5y3m Toll-like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D532 Y534 G563 H564 R588
Binding residue
(residue number reindexed from 1)		D469 Y471 G500 H501 R525
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
Biological Process
GO:0002224 toll-like receptor signaling pathway
GO:0006955 immune response
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5y3m, PDBe:5y3m, PDBj:5y3m
PDBsum5y3m
PubMed29625894
UniProtQ5I2M5|TLR9_BOVIN Toll-like receptor 9 (Gene Name=TLR9)

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