Structure of PDB 5xuz Chain A Binding Site BS02

Receptor Information
>5xuz Chain A (length=1216) Species: 1410628 (Lachnospiraceae bacterium ND2006) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHMSKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDY
KGVKKLLDRYYLSFINDVLHSIKLKNLNNYISLFRKKTRTEKENKELENL
EINLRKEIAKAFKGNEGYKSLFKKDIIETILPEFLDDKDEIALVNSFNGF
TTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNMDIFEKVDAIF
DKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTE
SGEKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSD
EEVLEVFRNTLNKNSEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTI
SKDIFGEWNVIRDKWNAEYDDIHLKVVTEKYEDDRRKSFKKIGSFSLEQL
QEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKLFDADFVLEKSLKKND
AVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDILLKV
DHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYG
SKYYLAIMDKKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSK
KWMAYYNPSEDIQKIYKNGTFKKGDMFNLNDCHKLIDFFKDSISRYPKWS
NAYDFNFSETEKYKDIAGFYREVEEQGYKVSFESASKKEVDKLVEEGKLY
MFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFMRRAS
LKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPI
AINKCPKNIFKINTEVRVLLKHDDNPYVIGIDRGERNLLYIVVVDGKGNI
VEQYSLNEIINNFNGIRIKTDYHSLLDKKEKERFEARQNWTSIENIKELK
AGYISQVVHKICELVEKYDAVIALEDLNSGFKNSRVKVEKQVYQKFEKML
IDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFIFYIPAWL
TSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYK
NFSRTDADYIKKWKLYSYGNRIRIDWEEVCLTSAYKELFNKYGINYQQGD
IRALLCEQSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGI
FYDSRNYEAQENAILPKNADANGAYNIARKVLWAIGQFKKAEDEKLDKVK
IAISNKEWLEYAQTSV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5xuz Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		N160 K167 S168 G242 K251 N256 E257 N260 S286 S288 Y290 K349 W355 R508 N509 T512 Q513 K514 D535 K538 Y542 L585 P587 M592 S599 K600 K601 Y646 K648 W649 S739 G740 N895 I896 K897 K945 S982 F983 K984
Binding residue
(residue number reindexed from 1)		N163 K170 S171 G245 K254 N259 E260 N263 S289 S291 Y293 K352 W358 R508 N509 T512 Q513 K514 D535 K538 Y542 L585 P587 M592 S599 K600 K601 Y646 K648 W649 S739 G740 N895 I896 K897 K945 S982 F983 K984
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5xuz, PDBe:5xuz, PDBj:5xuz
PDBsum5xuz
PubMed28781234
UniProtA0A182DWE3

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