Structure of PDB 5xus Chain A Binding Site BS02

Receptor Information
>5xus Chain A (length=1206) Species: 1410628 (Lachnospiraceae bacterium ND2006) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMSKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKG
VKKLLDRYYLSFINDVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEI
NLRKEIAKAFKGNEGYKSLFKKDIIETILPEFLDDKDEIALVNSFNGFTT
AFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNMDIFEKVDAIFDK
HEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG
EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEE
VLEVFRNTLNKNSEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISK
DIFGEWNVIRDKWNAEYDDIHLVTEKYEDDRRKSFKKIGSFSLEQLQEYA
DADLSVVEKLKEIIIQKVDEIYKVYGSSEKLFDADFVLEKSLKKNDAVVA
IMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDILLKVDHIY
DAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYY
LAIMDKKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMA
YYNPSEDIQKIYKNGTFKKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYD
FNFSETEKYKDIAGFYREVEEQGYKVSFESASKKEVDKLVEEGKLYMFQI
YNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFMRRASLKKE
ELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINK
CPKNIFKINTEVRVLLKHDDNPYVIGIDRGERNLLYIVVVDGKGNIVEQY
SLNEIINNFNGIRIKTDYHSLLDKKEKERFEARQNWTSIENIKELKAGYI
SQVVHKICELVEKYDAVIALEDLNVKVEKQVYQKFEKMLIDKLNYMVDKK
SNPCATGGALKGYQITNKFESFKSMSTQNGFIFYIPAWLTSKIDPSTGFV
NLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRTDADYIK
KWKLYSYGNRIRIFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCEQSD
KAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQ
ENAILPKNADANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLE
YAQTSV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5xus Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		N160 K167 S168 T169 G242 V245 K251 N256 E257 N260 S286 S288 Y290 K349 W355 N509 T512 Q513 K514 D535 D537 K538 Y542 L585 P587 K595 S599 K600 K601 Y646 W649 S739 G740 R883 N895 I896 K897 Q944 K945 S982 F983 K984
Binding residue
(residue number reindexed from 1)		N161 K168 S169 T170 G243 V246 K252 N257 E258 N261 S287 S289 Y291 K350 W356 N505 T508 Q509 K510 D531 D533 K534 Y538 L581 P583 K591 S595 K596 K597 Y642 W645 S735 G736 R879 N891 I892 K893 Q933 K934 S971 F972 K973
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5xus, PDBe:5xus, PDBj:5xus
PDBsum5xus
PubMed28781234
UniProtA0A182DWE3

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