Structure of PDB 5xoo Chain A Binding Site BS02

Receptor Information
>5xoo Chain A (length=349) Species: 6087 (Hydra vulgaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FNIHAWDVWHDMISVRALTVDSDVEIYKVLKAMSSAKITQATTGYKGTQL
KAMFSLDGPQIQNVVFKPKRYSRNKIILGTPYEGYDRHNAEIAAFHLDRL
LGFYRAPPVVGRYINLAAEVLPVAAKKLATTFIKDKDENLCFYGKCLYCN
RKEPACASNVTMEGALILWLPEKWPVLKLPHPWRRTYNKKMAKWETDSHY
CESVVIKEPYTKGPRLLDLIDTSIFDFLIGNADRHHYEYIENENGSMVIH
LDNAKSFGNPFVDEKSILSPLVQCCRLRSSTYNRLKIATSNENSLSVLLD
KRLSIDPIYPILTSDHLLALDRRLLLVQDAVEKCFKEKNKENVIIEDHL
Ligand information
Ligand IDGAL
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3+,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-FPRJBGLDSA-N
SMILES
SoftwareSMILES
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O
OpenEye OEToolkits 1.7.2C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
OpenEye OEToolkits 1.7.2C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
FormulaC6 H12 O6
Namebeta-D-galactopyranose;
beta-D-galactose;
D-galactose;
galactose
ChEMBLCHEMBL300520
DrugBank
ZINCZINC000002597049
PDB chain5xoo Chain C Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5xoo Structure and evolution of the Fam20 kinases
Resolution2.85 Å
Binding residue
(original residue number in PDB)		Q115 Y148 E149 G150 Y214
Binding residue
(residue number reindexed from 1)		Q49 Y82 E83 G84 Y148
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0046872 metal ion binding
Biological Process
GO:0006468 protein phosphorylation
GO:0016310 phosphorylation
Cellular Component
GO:0005794 Golgi apparatus
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5xoo, PDBe:5xoo, PDBj:5xoo
PDBsum5xoo
PubMed29572475
UniProtT2MHS6

[Back to BioLiP]