Structure of PDB 5xgl Chain A Binding Site BS02

Receptor Information
>5xgl Chain A (length=207) Species: 6500 (Aplysia californica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVD
LVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQV
LSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSG
FEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLV
VKFRERR
Ligand information
Receptor-Ligand Complex Structure
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PDB5xgl The crystal structure of Ac-AChBP in complex with alpha-conotoxin LvIA reveals the mechanism of its selectivity towards different nAChR subtypes
Resolution3.439 Å
Binding residue
(original residue number in PDB)
Q55 R77 V106 M114 I116 D162 S164 S165
Binding residue
(residue number reindexed from 1)
Q56 R78 V107 M115 I117 D163 S165 S166
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function

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Cellular Component
External links
PDB RCSB:5xgl, PDBe:5xgl, PDBj:5xgl
PDBsum5xgl
PubMed28585176
UniProtQ8WSF8

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