Structure of PDB 5xfn Chain A Binding Site BS02

Receptor Information
>5xfn Chain A (length=301) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPRPRLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLW
KDISPAALPGEELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPA
PSWVCRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLDWDAGHL
SNRQQSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLYGDRFYE
FECCVCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDREILPFT
SENWDSLLLGELSDTPKGERSSRLLSALNSHKDRFISGCLFGLHARMPPP
V
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5xfn Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5xfn Polycomb-like proteins link the PRC2 complex to CpG islands
Resolution1.9 Å
Binding residue
(original residue number in PDB)		C90 C93 H115 C118
Binding residue
(residue number reindexed from 1)		C65 C68 H90 C93
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5xfn, PDBe:5xfn, PDBj:5xfn
PDBsum5xfn
PubMed28869966
UniProtO43189|PHF1_HUMAN PHD finger protein 1 (Gene Name=PHF1)

[Back to BioLiP]