Structure of PDB 5x4k Chain A Binding Site BS02

Receptor Information
>5x4k Chain A (length=471) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHMDKEGFLNKVREAVDVVKLHIELGHTIRIISHRDADGITSAAILAKAL
GREGASFHISIVKQVSEDLLRELKDEDYKIFIFSALGSGSLSLIKEYLKE
KTVIILDHHPPENVKLEEKHILVNPVQFGANSVRDLSGSGVTYFFARELN
EKNRDLAYIAIVGAVGDMQENDGVFHGMNLDIIEDGKSLGILEVKKELRL
FGRETRPLYQMLAYATNPEIPEVTGDERKAIEWLKNKGFNPEKKYWELSE
EEKKKLHDFLIIHMIKHGAGKEDIDRLIGDVVISPLYPEGDPRHEAREFA
TLLNATGRLNLGNLGVAVCLGDEEAFRKALKMVEDYKREQIEARKWLLQN
WNSEVWEGDHVYVLYVGKSIRDTLVGIAASMAINAGLADPEKPVIVFADT
DEDPNLLKGSARTTERALAKGYNLGEALRKAAELVNGEGGGHAIAAGIRI
PRARLAEFRKLIDKILGEQVS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5x4k Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5x4k The crystal structure of Pyrococcus furiosus RecJ implicates it as an ancestor of eukaryotic Cdc45.
Resolution1.749 Å
Binding residue
(original residue number in PDB)		H32 D34
Binding residue
(residue number reindexed from 1)		H34 D36
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5x4k, PDBe:5x4k, PDBj:5x4k
PDBsum5x4k
PubMed30053256
UniProtQ8TZE0

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