Structure of PDB 5x2g Chain A Binding Site BS02

Receptor Information
>5x2g Chain A (length=749) Species: 192222 (Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MARILAFDIGISSIGWAFSENDELKDCGVRIFTKGESLALPRRLARSARK
RLARRKARLNHLKHLIANEFKLNYEDYQSFDESLAKAYKGSLISPYELRF
RALNELLSKQDFARVILHIAKRRGYDDIKNKEKGAILKAIKQNEEKLANY
QSVGEYLYKEYFQKFKENSKEFTNVRNKKESYERCIAQSFLKDELKLIFK
KQREFGFSFSKKFEEEVLSVAFYKRALKDFSHLVGNCSFFTDEKRAPKNS
PLAFMFVALTRIINLLNNLKNTEGILYTKDDLNALLNEVLKNGTLTYKQT
KKLLGLSDDYEFKGEKGTYFIEFKKYKEFISQDDLNEIAKDITLIKDEIK
LKKALAKYDLNQNQIDSLSKLEFKDHLNISFKALKLVTPLMLEGKKYDEA
CNELNLKVAINEDKKDFLPAFNETYYKDEVTNPVVLRAIKEYRKVLNALL
KKYGKVHKINIELGGGYIARLVLNYTKDYLDFLPLSDVHVEAKSGMLTSA
LRHTWGFSAKDRNNHLHHAIDAVIIAYRQKVLDKIDEIFVSKPERKKPSG
ALHEETFRKEEEFYQSYGGKEGVLKALELGKIRKVNGKIVKNGDMFRVDI
FKHKKTNKFYAVPIYTMDFALKVLPNKAVARSKKGEIKDWILMDENYEFC
FSLYKDSLILIQTKDMQEPEFVYYNAFTSSTVSLIVSKHDNKFETLSKNQ
KILFKNANEKEVIAKSIGIQNLKVFEKYIVSALGEVTKAEFRQREDFKK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5x2g Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems
Resolution2.4 Å
Binding residue
(original residue number in PDB)		Y131 K135 G143 I145 L146 Y191 L236 F239 L242 G244 R254 N273 N277 N280 E320 K363 D392 H393 K413 D415 E446 Y642 E790 T791 R793 R866 T916 K940 S951
Binding residue
(residue number reindexed from 1)		Y125 K129 G134 I136 L137 Y182 L227 F230 L233 G235 R245 N264 N268 N271 E311 K346 D375 H376 K396 D398 E429 Y467 E555 T556 R558 R631 T681 K705 S716
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:5x2g, PDBe:5x2g, PDBj:5x2g
PDBsum5x2g
PubMed28306506
UniProtQ0P897|CAS9_CAMJE CRISPR-associated endonuclease Cas9 (Gene Name=cas9)

[Back to BioLiP]