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Receptor Information

>5wzp Chain A (length=603) Species: 1681 (Bifidobacterium bifidum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MMQFTMSGTMLRFDETTLRFSFSRDGATWSGCDGIEPQLTRESFSFAGAA
TVTHERIETGTGVGVRSVFAGFADYAFETYIWIERSSGDVLCEWVPLRID
RVLWPAPLSFDRADAHDVTLITHEQGVMIPNSWPTEVGTDAVSFGGRFET
AGGYMPWFAQLRSDGHAYIAICETPWNAGYDIDHPAGGPYTHVGMWFEPS
LGRMDYRRVVRYRLLDHADHTAICKTYRAYVNERGRLRTLAEKAARNPSV
RDLLGRSWVHVGIKTNVQPDSSFYDPAQPGKNDSLVTFAQRERQMRTLHE
MGAGRLYLHLDGWAQPGYDNGHPDYLPACREAGGWKGMKSLIDACHEQGD
LFGTHDQYRDYYFAARTFDPRNAIRLADGTMPEHAMWAGGRQTYLCAELA
PDYVRRNFSEIATHGIVLDCAYLDVFTCNEGDECSHPEHRMTRRECYERR
AECFEYLLAHGILTSSEEVSDWAVPSLVFCHYAPYDFQMRSPDAPRHGIP
VPLYNLVYHDCVIQPWMMDRVAGGDDYMLYALLNGGAPYLIRDAAYTEND
IERCAVVAGLHRRVGMQELVRHDLVGGDPLVQRSVFADGTAVTCDFHAQT
YEV

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

5wzp Chain A Residue 702 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5wzp The first crystal structure of a family 129 glycoside hydrolase from a probiotic bacterium reveals critical residues and metal cofactors
Resolution	2.64 Å
Binding residue (original residue number in PDB)	H271 H320 D322 H366
Binding residue (residue number reindexed from 1)	H260 H309 D311 H355
Annotation score	4

Enzyme Commision number

3.2.1.-

	Molecular Function
GO:0016798	hydrolase activity, acting on glycosyl bonds
GO:0033926	endo-alpha-N-acetylgalactosaminidase activity
GO:0046872	metal ion binding

PDB	RCSB:5wzp, PDBe:5wzp, PDBj:5wzp
PDBsum	5wzp
PubMed	28546425
UniProt	G5ELM1

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Structure of PDB 5wzp Chain A Binding Site BS02