Structure of PDB 5wu4 Chain A Binding Site BS02

Receptor Information
>5wu4 Chain A (length=485) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DSHQLAKALAEAADVGAQMIKLVGLRELSEAERQLRSLVVALMQEVFTEF
FPGCVVHPFGSSINSFDVHGCDLDLFLDLETPKEEKAEGAAMLELVGSIL
RGCVPGVYRVQTVPSARRPVVKFAHRPSGLHGDVSLSNRLALHNSRFLSL
CSELDGRVRPLVYTLRAWAQGRGLSGSGPLLSNYALTLLVIYFLQTRDPP
VLPTVSQLTQKAGEGEQVEVDGWDCSFPRDASRLEPSINVEPLSSLLAQF
FSAVSSWDLRGSLLSLREGQALPVAGGLPSNLWEGLRLGPLNLQDPFDLS
HNVAANVTSRVAGRLQNCCRAAANYCRSLQYQRRSSRGRDWGLLPLLQPS
SPSSLLSATPIPLPLAPFTQLTAALVQVFREALGCHIEQSASWRCALWHR
VWQGRRRARRRLQQQTKEGGWLATEAQVTQELKTEPLLSFVASVSPADRM
LTVTPLQDPQGLFPDLHHFLQVFLPQAIRHLKLEH
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5wu4 Chain A Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5wu4 Crystal structures of U6 snRNA-specific terminal uridylyltransferase
Resolution2.8 Å
Binding residue
(original residue number in PDB)		S205 D216 D218
Binding residue
(residue number reindexed from 1)		S61 D72 D74
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.19: polynucleotide adenylyltransferase.
2.7.7.52: RNA uridylyltransferase.
External links
PDB RCSB:5wu4, PDBe:5wu4, PDBj:5wu4
PDBsum5wu4
PubMed28589955
UniProtQ9H6E5|STPAP_HUMAN Speckle targeted PIP5K1A-regulated poly(A) polymerase (Gene Name=TUT1)

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