Structure of PDB 5wmb Chain A Binding Site BS02

Receptor Information
>5wmb Chain A (length=433) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RIVACDDPDFLTSYFAHSRLHHLSAWKANLKDKFLNENIHKYTKITDKDT
YIIFHIDFDCFFATVAYLCRSSSFSACDFKRDPIVVCHGTKNSDIASCNY
VARSYGIKNGMWVSQAEKMLPNGIKLISLPYTFEQFQLKSEAFYSTLKRL
NIFNLILPISIDEAVCVRIIPDNIHNTNTLNARLCEEIRQEIFQGTNGCT
VSIGCSDSLVLARLALKMAKPNGYNITFKSNLSEEFWSSFKLDDLPGVGH
STLSRLESTFDSPHSLNDLRKRYTLDALKASVGSKLGMKIHLALQGQDDE
ESLKILYDPKEVLQRKSLSIDINWGIRFKNITQVDLFIERGCQYLLEKLN
EINKTTSQITLKLMRRCKDAPIEPPKYMGMGRCDSFSRSSRLGIPTNEFG
IIATEMKSLYRTLGCPPMELRGLALQFNKLVDV
Ligand information
Receptor-Ligand Complex Structure
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PDB5wmb Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase.
Resolution2.25 Å
Binding residue
(original residue number in PDB)		I307 Y319 F320 H322 S323 R324 L325 H326 S329 H393 G394 K396 N397 S398 D399 K590 R620 K621 L623 S624 I625 D626 I627 N628 W629 K681 Y682 G684 M685
Binding residue
(residue number reindexed from 1)		I2 Y14 F15 H17 S18 R19 L20 H21 S24 H88 G89 K91 N92 S93 D94 K285 R315 K316 L318 S319 I320 D321 I322 N323 W324 K376 Y377 G379 M380
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:5wmb, PDBe:5wmb, PDBj:5wmb
PDBsum5wmb
PubMed29042535
UniProtP12689|REV1_YEAST DNA repair protein REV1 (Gene Name=REV1)

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