Structure of PDB 5wm8 Chain A Binding Site BS02

Receptor Information
>5wm8 Chain A (length=432) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IVACDDPDFLTSYFAHSRLHHLSAWKANLKDKFLNENIHKYTKITDKDTY
IIFHIDFDCFFATVAYLCRSSSFSACDFKRDPIVVCHGTKNSDIASCNYV
ARSYGIKNGMWVSQAEKMLPNGIKLISLPYTFEQFQLKSEAFYSTLKRLN
IFNLILPISIDEAVCVRIIPDNIHNTNTLNARLCEEIRQEIFQGTNGCTV
SIGCSDSLVLARLALKMAKPNGYNITFKSNLSEEFWSSFKLDDLPGVGHS
TLSRLESTFDSPHSLNDLRKRYTLDALKASVGSKLGMKIHLALQGQDDEE
SLKILYDPKEVLQRKSLSIDINWGIRFKNITQVDLFIERGCQYLLEKLNE
INKTTSQITLKLMRRCKDAPIEPPKYMGMGRCDSFSRSSRLGIPTNEFGI
IATEMKSLYRTLGCPPMELRGLALQFNKLVDV
Ligand information
Receptor-Ligand Complex Structure
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PDB5wm8 Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase.
Resolution1.92 Å
Binding residue
(original residue number in PDB)		I307 Y319 F320 H322 S323 R324 L325 H326 S329 H393 G394 T395 K396 N397 S398 D399 K590 R620 K621 S624 I625 D626 I627 N628 W629 Y682 G684 M685 G686
Binding residue
(residue number reindexed from 1)		I1 Y13 F14 H16 S17 R18 L19 H20 S23 H87 G88 T89 K90 N91 S92 D93 K284 R314 K315 S318 I319 D320 I321 N322 W323 Y376 G378 M379 G380
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:5wm8, PDBe:5wm8, PDBj:5wm8
PDBsum5wm8
PubMed29042535
UniProtP12689|REV1_YEAST DNA repair protein REV1 (Gene Name=REV1)

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