Structure of PDB 5wjm Chain A Binding Site BS02

Receptor Information
>5wjm Chain A (length=216) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DNVPTFPRDYEGPFDVTEGQPGPRVWTFLAHDRDSGPNGQVEYSVVDGDP
LGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGVPPLSSTMLVG
IRVLDINDNDPVLLNLPMNVTISENSPVSSFVAHVLASDADSGCNALLTF
NITAGNRERAFFINATTGIVTVNRPLDRERIPEYRLTVSVKDNPENPRIA
RKDFDLLLVSLADEND
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5wjm Chain A Residue 2002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5wjm Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		E1733 D1787 E1789 D1823
Binding residue
(residue number reindexed from 1)		E18 D72 E74 D108
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5wjm, PDBe:5wjm, PDBj:5wjm
PDBsum5wjm
PubMed30033219
UniProtQ99PF4|CAD23_MOUSE Cadherin-23 (Gene Name=Cdh23)

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