Structure of PDB 5w0o Chain A Binding Site BS02

Receptor Information
>5w0o Chain A (length=338) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQD
FPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLGLDCVRTIEELARVLRKH
SGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAI
DPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIP
VLQEIPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYT
EEFDFKEHVISIRRKSLLTTFKKQWTSIVIEDPFDLNHNLGAGLSRKMTN
FIMKAFINGRRVFGIPVKGFPKDYPSKMEYFFDPDVLT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5w0o Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Resolution2.488 Å
Binding residue
(original residue number in PDB)		L1097 I1099 R1165
Binding residue
(residue number reindexed from 1)		L107 I109 R175
Enzymatic activity
Enzyme Commision number 2.7.7.52: RNA uridylyltransferase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:5w0o, PDBe:5w0o, PDBj:5w0o
PDBsum5w0o
PubMed28671666
UniProtQ5VYS8|TUT7_HUMAN Terminal uridylyltransferase 7 (Gene Name=TUT7)

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