Structure of PDB 5vvu Chain A Binding Site BS02
Receptor Information
>5vvu Chain A (length=424) Species:
9606
(Homo sapiens) [
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HFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWR
EMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKL
DQVSQFGCRSFALLFDNIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGE
PETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKE
IPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLK
GVLTNPNCEFEANYVAIHTLATWYKYSPQMALKLALTEWLQEFGVPHQYS
VTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVIEEWRSRAAK
FEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGC
RSWAFRGGLAGEFQRLLPIDGAND
Ligand information
>5vvu Chain D (length=4) Species:
9606
(Homo sapiens) [
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PYSS
Receptor-Ligand Complex Structure
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PDB
5vvu
Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Resolution
2.7 Å
Binding residue
(original residue number in PDB)
F625 W645
Binding residue
(residue number reindexed from 1)
F362 W382
Enzymatic activity
Enzyme Commision number
3.2.1.169
: protein O-GlcNAcase.
External links
PDB
RCSB:5vvu
,
PDBe:5vvu
,
PDBj:5vvu
PDBsum
5vvu
PubMed
28939839
UniProt
O60502
|OGA_HUMAN Protein O-GlcNAcase (Gene Name=OGA)
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