BioLiP

Receptor Information

>5vu6 Chain A (length=756) Species: 311400 (Thermococcus kodakarensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MILDTDYITEDGKPVIRIFKKENGEFKIEYDRTFEPYFYALLKDDSAIEE
VKKITAERHGTVVTVKRVEKVQKKFLGRPVEVWKLYFTHPQDVPAIRDKI
REHPAVIDIYEYDIPFAKRYLIDKGLVPMEGDEELKMLAFAIATLYHEGE
EFAEGPILMISYADEEGARVITWKNVDLPYVDVVSTEREMIKRFLRVVKE
KDPDVLITYNGDNFDFAYLKKRCEKLGINFALGRDGSEPKIQRMGDRFAV
EVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGQPKEKVYAEEITTAWE
TGENLERVARYSMEDAKVTYELGKEFLPMEAQLSRLIGQSLWDVSRSSTG
NLVEWFLLRKAYERNELAPNKPDEKELARRRQSYEGGYVKEPERGLWENI
VYLDFRSLYPSIIITHNVSPDTLNREGCKEYDVAPQVGHRFCKDFPGFIP
SLLGDLLEERQKIKKKMKATIDPIERKLLDYRQRRIKILANSYYGYYGYA
RARWYCKECAESVTAWGREYITMTIKEIEEKYGFKVIYSDTDGFFATIPG
ADAETVKKKAMEFLKYINAKLPGALELEYEGFYKRGFFVTKKKYAVIDEE
GKITTRGLEIVRRDWSEIAKETQARVLEALLKDGDVEKAVRIVKEVTEKL
SKYEVPPEKLVIHIQITRDLKDYKATGPHVAVAKRLAARGVKIRPGTVIS
YIVLKGSGRIGDRAIPFDEFDPTKHKYDAEYYIENQVLPAVERILRAFGY
RKEDLR

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5vu6 Structural basis for TNA synthesis by an engineered TNA polymerase.
Resolution	3.0 Å
Binding residue (original residue number in PDB)	D540 K592 R606 G607 V611 R612 R613 I664 Q665 T667 R668 Y673 K674 A675 H679
Binding residue (residue number reindexed from 1)	D540 K592 R606 G607 V611 R612 R613 I664 Q665 T667 R668 Y673 K674 A675 H679

Enzyme Commision number

2.7.7.7: DNA-directed DNA polymerase.

	Molecular Function
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003887	DNA-directed DNA polymerase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006260	DNA replication
GO:0071897	DNA biosynthetic process

PDB	RCSB:5vu6, PDBe:5vu6, PDBj:5vu6
PDBsum	5vu6
PubMed	29180809
UniProt	D0VWU9

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Structure of PDB 5vu6 Chain A Binding Site BS02