Structure of PDB 5vcu Chain A Binding Site BS02

Receptor Information
>5vcu Chain A (length=186) Species: 5763 (Naegleria fowleri) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MESIKCVVVGDGAVGKTALLIAYSSGCFPEDYVPTVFDNYNKNIPYGDGI
VSIALYDTAGQEDYDRLRPLSYPDTDVFLVCFSLENPNSLENCHSKWAEE
LKHYNPDTPIVLVGTKLDLKKDEEYVKKLKEKKISPVTTEQGQEMKDKIK
ACGYIECSAKTMENLTEAFNMAIDIAMKQRLKDAPP
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5vcu Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5vcu Crystal structure of ras-related c3 botulinum toxin substrate 1 isoform x2 from Naegleria fowleri in complex with GDP
Resolution1.85 Å
Binding residue
(original residue number in PDB)		T17 T35
Binding residue
(residue number reindexed from 1)		T17 T35
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0046872 metal ion binding
Biological Process
GO:0007264 small GTPase-mediated signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:5vcu, PDBe:5vcu, PDBj:5vcu
PDBsum5vcu
PubMed
UniProtA0A1Z0YU85

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