Structure of PDB 5uv2 Chain A Binding Site BS02

Receptor Information
>5uv2 Chain A (length=514) Species: 2711 (Citrus sinensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIWDHDFLQSLNSNYTDETYKRRAEELKGKVKTAIKDVTEPLDQLELIDN
LQRLGLAYHFEPEIRNILRNIHNHNKDYNWRKENLYATSLEFRLLRQHGY
PVSQEVFSGFKDDKVGFICDDFKGILSLHEASYYSLEGESIMEEAWQFTS
KHLKEMMIDVFVAEQAKRALELPLHWKAPMLEARWFIHVYEKREDKNHLL
LELAKLEFNTLQAIYQEELKDISGWWKDTGLGEKLSFARNRLVASFLWSM
GIAFEPQFAYCRRVLTISIALITVIDDIYDVYGTLDELEIFTDAVARWDI
NYALKHLPGYMKMCFLALYNFVNEFAYYVLKQQDFDMLLSIKHAWLGLIQ
AYLVEAKWYHSKYTPKLEEYLENGLVSITGPLIITISYLSGTNPIIKKEL
EFLESNPDIVHWSSKIFRLQDDLGTSSDEIQRGDVPKSIQCYMHETGASE
EVAREHIKDMMRQMWKKVNAYTADKDSPLTRTTAEFLLNLVRMSHFMYLH
GDVGFTLLFQPIPL
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain5uv2 Chain A Residue 702 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5uv2 Structural Characterization of Early Michaelis Complexes in the Reaction Catalyzed by (+)-Limonene Synthase from Citrus sinensis Using Fluorinated Substrate Analogues.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		D343 D347
Binding residue
(residue number reindexed from 1)		D276 D280
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) R306 W315 I336 D343 D347 S444 I445 T446 R485 D488 T492 E496 Y565
Catalytic site (residue number reindexed from 1) R239 W248 I269 D276 D280 S377 I378 T379 R418 D421 T425 E429 Y498
Enzyme Commision number 4.2.3.20: (R)-limonene synthase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0010333 terpene synthase activity
GO:0016829 lyase activity
GO:0034002 (R)-limonene synthase activity
GO:0046872 metal ion binding
Biological Process
GO:0016102 diterpenoid biosynthetic process
Cellular Component
GO:0009507 chloroplast

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5uv2, PDBe:5uv2, PDBj:5uv2
PDBsum5uv2
PubMed28272876
UniProtA0A1C9J6A7|RLC1_CITSI (R)-limonene synthase 1, chloroplastic

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