Structure of PDB 5uu7 Chain A Binding Site BS02
Receptor Information
>5uu7 Chain A (length=316) Species:
1427
(Bacillus thermoproteolyticus) [
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ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTL
PGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAI
RSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTD
YTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGD
SLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTH
YGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTS
QEVASVKQAFDAVGVK
Ligand information
Ligand ID
ZN
InChI
InChI=1S/Zn/q+2
InChIKey
PTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
Formula
Zn
Name
ZINC ION
ChEMBL
CHEMBL1236970
DrugBank
DB14532
ZINC
PDB chain
5uu7 Chain A Residue 402 [
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Receptor-Ligand Complex Structure
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PDB
5uu7
The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order.
Resolution
1.60001 Å
Binding residue
(original residue number in PDB)
E177 N183 D185 E190
Binding residue
(residue number reindexed from 1)
E177 N183 D185 E190
Annotation score
4
Enzymatic activity
Catalytic site (original residue number in PDB)
H142 E143 H146 Y157 E166 D226 H231
Catalytic site (residue number reindexed from 1)
H142 E143 H146 Y157 E166 D226 H231
Enzyme Commision number
3.4.24.27
: thermolysin.
Gene Ontology
Molecular Function
GO:0004222
metalloendopeptidase activity
Biological Process
GO:0006508
proteolysis
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:5uu7
,
PDBe:5uu7
,
PDBj:5uu7
PDBsum
5uu7
PubMed
30198901
UniProt
P00800
|THER_BACTH Thermolysin (Gene Name=npr)
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