Structure of PDB 5uj7 Chain A Binding Site BS02

Receptor Information
>5uj7 Chain A (length=337) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTG
KTATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTG
QKATANHAAELLAKQFCTTVLLVDELDLLWTHKQDIMYNLFDWPTHKEAR
LVVLAIANTMDLPERTRMCFQPYTYSQLQQILRSRLKHLKIQLVARKVAA
LSGDARRCLDICRRATEICEFVTIAHSMEAVDEMFSSSYITAIKNSSVLE
QSFLRAILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCS
HLGSCRLLLVEPSRNDLLLRVRLNVSQDDVLYALKDE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5uj7 Chain A Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5uj7 Structure of the active form of human Origin Recognition Complex and its ATPase motor module.
Resolution3.394 Å
Binding residue
(original residue number in PDB)		T541 D620
Binding residue
(residue number reindexed from 1)		T52 D124
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:5uj7, PDBe:5uj7, PDBj:5uj7
PDBsum5uj7
PubMed28112645
UniProtQ13415|ORC1_HUMAN Origin recognition complex subunit 1 (Gene Name=ORC1)

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