Structure of PDB 5uie Chain A Binding Site BS02

Receptor Information
>5uie Chain A (length=312) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALSSAILSEKPNVKWEDVAGLEGAKEALKEAVILPVKFPHLFKGNRKPTS
GILLYGPPGTGKSYLAKAVATEANSTFFSVSSSDLVSKWMGESEKLVKQL
FAMARENKPSIIFIDEVDALTGTRGEGESEASRRIKTELLVQMNGVGNDS
QGVLVLGATNIPWQLDSAIRRRFERRIYIPLPDLAARTTMFEINVGDTPC
VLTKEDYRTLGAMTEGYSGSDIAVVVKDALMQPIRKIQSATHFKDVSETR
KLTPCSPGDDGAIEMSWTDIEADELKEPDLTIKDFLKAIKSTRPTVNEDD
LLKQEQFTRDFG
Ligand information
Ligand IDBEF
InChIInChI=1S/Be.3FH/h;3*1H/q+2;;;/p-3
InChIKeyOGIAHMCCNXDTIE-UHFFFAOYSA-K
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[Be-](F)(F)F
ACDLabs 10.04
CACTVS 3.341		F[Be-](F)F
FormulaBe F3
NameBERYLLIUM TRIFLUORIDE ION
ChEMBL
DrugBank
ZINC
PDB chain5uie Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5uie Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase.
Resolution5.7 Å
Binding residue
(original residue number in PDB)		G176 K179 N277
Binding residue
(residue number reindexed from 1)		G59 K62 N160
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0001778 plasma membrane repair
GO:0006914 autophagy
GO:0006997 nucleus organization
GO:0007033 vacuole organization
GO:0015031 protein transport
GO:0016125 sterol metabolic process
GO:0016197 endosomal transport
GO:0016236 macroautophagy
GO:0031468 nuclear membrane reassembly
GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway
GO:0036258 multivesicular body assembly
GO:0045053 protein retention in Golgi apparatus
GO:0045324 late endosome to vacuole transport
GO:0061709 reticulophagy
GO:0061764 late endosome to lysosome transport via multivesicular body sorting pathway
GO:0061952 midbody abscission
GO:0070676 intralumenal vesicle formation
GO:0071985 multivesicular body sorting pathway
GO:0090148 membrane fission
GO:0097352 autophagosome maturation
Cellular Component
GO:0005643 nuclear pore
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0030496 midbody
GO:1904949 ATPase complex
GO:1990621 ESCRT IV complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5uie, PDBe:5uie, PDBj:5uie
PDBsum5uie
PubMed28379137
UniProtP52917|VPS4_YEAST Vacuolar protein sorting-associated protein 4 (Gene Name=VPS4)

[Back to BioLiP]