Structure of PDB 5ub8 Chain A Binding Site BS02

Receptor Information

>5ub8 Chain A (length=174) Species: 237561 (Candida albicans SC5314) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

YSYDYEYLYKIVLIGDSGVGKSNLLSRFTRDEFNLEGVEFATRTLEIDGK
RVKAQIWDTAGQERYRAITSAYYRGAVGALIVYDIAKTESYESVSRWLKE
LKEHADANIIIELVGNKSDLDHLRAVPTEEAKNFAMENNLLFTEASALSS
DNVDLSFHQLLKNIYEMISKHQLE

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

5ub8 Chain A Residue 303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5ub8 Crystal structure of YPT31, a Rab family GTPase from Candida albicans, in complex with GDP and Zn(II)
Resolution	2.35 Å
Binding residue (original residue number in PDB)	E112 H116
Binding residue (residue number reindexed from 1)	E100 H104
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003924	GTPase activity
GO:0005525	GTP binding
GO:0046872	metal ion binding

	Biological Process
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006887	exocytosis
GO:0042273	ribosomal large subunit biogenesis

	Cellular Component
GO:0005794	Golgi apparatus
GO:0031521	spitzenkorper
GO:0055037	recycling endosome
GO:1903561	extracellular vesicle

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Cellular Component

External links

PDB	RCSB:5ub8, PDBe:5ub8, PDBj:5ub8
PDBsum	5ub8
PubMed
UniProt	A0A1D8PTI2

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