Structure of PDB 5uas Chain A Binding Site BS02

Receptor Information
>5uas Chain A (length=440) Species: 1547444 (Pseudoalteromonas sp. PLSV) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DRQVGYFADNGVGNPLAIVQHPAGIHKNGITYVSYQGPKEDPYIASYNHQ
TGQWQGPFRAGISELGRRDGGKKFDNNGKPTMLIDDEGYIHIFYGGHGGQ
ASNGKNPLGNTHHGANKHAVSKRPYDISQWEDLNNITPFGTYNQAIKMDN
GDIYLFFRHGAHRSDWVYQKSVDNGRTFASPVSFLKHKRRTDIDAVDSWY
AWAGKGQGDNIIVSYDYHVCWDGGAGVNGRGHTTERHDVYFMSFNTKTGE
WSNVEGEKLVLPVTREVADEKTMAMRTGELWTFNGSTHLDAQGQPHIAIN
AGIDKGAKTGGPKQTRHVRWNGNEWVGGDKVIPQYERVSRGDFMVTDPEN
IRYLTTYNQDNDAVLSWWQSHDGGEHFVEDKTVLRKDNASFAISAFIKDA
IPDAQMLVAEKVSDEGIKMYLVGEEGAVTRSLVDLKTAMP
Ligand information
Ligand IDBDP
InChIInChI=1S/C6H10O7/c7-1-2(8)4(5(10)11)13-6(12)3(1)9/h1-4,6-9,12H,(H,10,11)/t1-,2-,3+,4-,6+/m0/s1
InChIKeyAEMOLEFTQBMNLQ-QIUUJYRFSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0[C@@H]1([C@@H]([C@H](O[C@H]([C@@H]1O)O)C(=O)O)O)O
OpenEye OEToolkits 1.7.0C1(C(C(OC(C1O)O)C(=O)O)O)O
CACTVS 3.370O[CH]1O[CH]([CH](O)[CH](O)[CH]1O)C(O)=O
ACDLabs 12.01O=C(O)C1OC(O)C(O)C(O)C1O
CACTVS 3.370O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O
FormulaC6 H10 O7
Namebeta-D-glucopyranuronic acid;
beta-D-glucuronic acid;
D-glucuronic acid;
glucuronic acid
ChEMBLCHEMBL1159524
DrugBankDB03156
ZINCZINC000004097543
PDB chain5uas Chain C Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5uas New Ulvan-Degrading Polysaccharide Lyase Family: Structure and Catalytic Mechanism Suggests Convergent Evolution of Active Site Architecture.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		H143 Y188 R204 H208 Y246
Binding residue
(residue number reindexed from 1)		H97 Y142 R158 H162 Y200
Annotation score4
Enzymatic activity
Enzyme Commision number 4.2.2.-
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0046872 metal ion binding
Cellular Component
GO:0005886 plasma membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:5uas, PDBe:5uas, PDBj:5uas
PDBsum5uas
PubMed28290654
UniProtA0A1W2VMZ5|UL25_PSEXP Ulvan Lyase-PL25 (Gene Name=PLSV_3936)

[Back to BioLiP]