Structure of PDB 5t8z Chain A Binding Site BS02

Receptor Information
>5t8z Chain A (length=161) Species: 395019 (Burkholderia multivorans ATCC 17616) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMIREILKMGDPRLLEVARPVDRFDTPELHEIVADMFETMHHANGAGLAA
PQIGIGLQIIIFGFPPVPETVLINPKLEYMPPDMEEGWEGCLSVPGMRGV
VSRYAKVRYSGFDQFGAKIDRVAEGFHARVVQHEYDHLIGKLYPMRITDF
TRFGFTEVLFP
Ligand information
Ligand IDFE2
InChIInChI=1S/Fe/q+2
InChIKeyCWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Fe+2]
CACTVS 3.341[Fe++]
FormulaFe
NameFE (II) ION
ChEMBL
DrugBankDB14510
ZINC
PDB chain5t8z Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5t8z Crystal structure of a peptide deformylase from Burkholderia multivorans in complex with actinonin
Resolution1.85 Å
Binding residue
(original residue number in PDB)		Q51 C99 H141 H145
Binding residue
(residue number reindexed from 1)		Q52 C91 H133 H137
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) G46 Q51 C99 L100 H141 E142 H145
Catalytic site (residue number reindexed from 1) G47 Q52 C91 L92 H133 E134 H137
Enzyme Commision number 3.5.1.88: peptide deformylase.
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0042586 peptide deformylase activity
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0018206 peptidyl-methionine modification

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Molecular Function
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Biological Process
External links
PDB RCSB:5t8z, PDBe:5t8z, PDBj:5t8z
PDBsum5t8z
PubMed
UniProtA0A0H3KPJ9

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