Structure of PDB 5t77 Chain A Binding Site BS02

Receptor Information
>5t77 Chain A (length=467) Species: 484019 (Thermosipho africanus TCF52B) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LFSSILFSIATFFSRILGLFRDVLFAKYFGVSYELDAYFIAIMFPFFLRK
VFGEGAMSSAFVPLYSEKSGEEKDKFLSSVINGFSLIILALVILSYFFPE
LIINLFGAGSSHETKILAKKLLLITSPSIYFIFLWAISYSILNTNNKFFW
PALTPSISNITIIIGTFLSTKYGIISPTIGFLIGSILMFFSIIKSIIKHK
YYFTIKHFPHFLKLFFPTFMTMVVSQINTVVDMNVVSFYDKGSISYLQYA
SRFYLLPYGLFAVSVSTVVLSKISNDRKNFNYHLNDALKTTLFFTIPSMV
GLIFLSTPIIRFFYEHGAFTSKDTLITSKILIAYTLGLPFYGIYSTISRS
YHAIKNTKTPFIAATIVSLSNIILDIIFGLKYGPIGVALATSIAGIIGVL
YLLFSVKTFPIKDFLKISLNSLIMLFVIYLTDFTDNEFWFLIQILIGILV
YLIFSSIFYRDLIRRFL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5t77 Chain A Residue 507 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5t77 Crystal structure of the MOP flippase MurJ in an inward-facing conformation.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		E74 D77
Binding residue
(residue number reindexed from 1)		E71 D74
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015648 lipid-linked peptidoglycan transporter activity
Biological Process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0015836 lipid-linked peptidoglycan transport
GO:0034204 lipid translocation
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5t77, PDBe:5t77, PDBj:5t77
PDBsum5t77
PubMed28024149
UniProtB7IE18|MURJ_THEAB Lipid II flippase MurJ (Gene Name=murJ)

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