Structure of PDB 5t16 Chain A Binding Site BS02

Receptor Information
>5t16 Chain A (length=276) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YDPTKAGDIVKATKWPPKLPEIQDLAIRARVFIHKSTIKDKVYLSGSEMI
NAHNERLEFLGDSILNSVMTLIIYNKFPDYSEGQLSTLRMNLVSNEQIKQ
WSIMYNFHEKLKTNFDLKDENSNFQNGKLKLYADVFEAYIGGLMEDDPRN
NLPKIRKWLRKLAKPVIEEATRNQVALEKTDKLDMNAKRQLYSLIGYASL
RLHYVTVKKPTAVDPNSIVECRVGDGTVLGTGVGRNIKIAGIRAAENALR
DKKMLDFYAKQRAAIPRSESVLKDPS
Ligand information
>5t16 Chain H (length=34) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gccaugucaugucaugaguccauggcauggcaug
..<<<<<<<<<<<<<<....>>>>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB5t16 The Functional Cycle of Rnt1p: Five Consecutive Steps of Double-Stranded RNA Processing by a Eukaryotic RNase III.
Resolution2.783 Å
Binding residue
(original residue number in PDB)		H217 K218 K222 F298 N306 F307 K311 K313
Binding residue
(residue number reindexed from 1)		H34 K35 K39 F115 N123 F124 K128 K130
Enzymatic activity
Enzyme Commision number 3.1.26.3: ribonuclease III.
Gene Ontology
Molecular Function
GO:0003725 double-stranded RNA binding
GO:0004525 ribonuclease III activity
Biological Process
GO:0006364 rRNA processing
GO:0006396 RNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:5t16, PDBe:5t16, PDBj:5t16
PDBsum5t16
PubMed28111020
UniProtQ02555|RNT1_YEAST Ribonuclease 3 (Gene Name=RNT1)

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