Structure of PDB 5oqt Chain A Binding Site BS02

Receptor Information
>5oqt Chain A (length=456) Species: 235909 (Geobacillus kaustophilus HTA426) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LFRKKPIQLLMKESGAKGASLRKELGAFDLTMLGIGAIIGTGIFVLTGVA
AAEHAGPALVLSFILSGLACVFAALCYAEFASTVPVSGSAYTYSYATFGE
LIAWILGWDLILEYGVASSAVAVGWSGYFQGLLSGELPKALTSAYDPAKG
TFIDLPAIIIVLFITFLLNLGAKKSARFNAVIVAIKVAVVLLFLAVGVWY
VKPENWTPFMPYGFSGVATGAATVFFAYIGFDAVSTAAEEVRNPQRDMPI
GIIVSLLVCTLLYIAVSLVLTGIVPYEQLNVKNPVAFALNYIHQDWVAGF
ISLGAIAGITTVLLVMMYGQTRLFYAISRDGLLPKVFARISPTRQVPYVN
TWLTGAAVAVFAGIIPLNKLAELTNIGTLFAFITVSIGVLVLRKTQPDLK
RAFRVPFVPVVPILAVLFCGYLVLQLPAMTWIGFVSWLLIGLVIYFIYGR
KHSELN
Ligand information
Ligand IDALA
InChIInChI=1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1
InChIKeyQNAYBMKLOCPYGJ-REOHCLBHSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0CC(C(=O)O)N
CACTVS 3.341C[CH](N)C(O)=O
ACDLabs 10.04O=C(O)C(N)C
CACTVS 3.341C[C@H](N)C(O)=O
OpenEye OEToolkits 1.5.0C[C@@H](C(=O)O)N
FormulaC3 H7 N O2
NameALANINE
ChEMBLCHEMBL279597
DrugBankDB00160
ZINCZINC000004658553
PDB chain5oqt Chain A Residue 515 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5oqt Structural basis for amino acid transport by the CAT family of SLC7 transporters.
Resolution2.86 Å
Binding residue
(original residue number in PDB)		I40 G42 T43 G44 F231 A232 I234
Binding residue
(residue number reindexed from 1)		I38 G40 T41 G42 F226 A227 I229
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015171 amino acid transmembrane transporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0003333 amino acid transmembrane transport
GO:0006865 amino acid transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5oqt, PDBe:5oqt, PDBj:5oqt
PDBsum5oqt
PubMed29416041
UniProtQ5L1G5

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