Structure of PDB 5oha Chain A Binding Site BS02

Receptor Information
>5oha Chain A (length=105) Species: 55518 (Magnetospirillum gryphiswaldense) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASIFRCRQCGQTISRRDWLLPMGGDHEHVVFNPAGMIFRVWCFSLAQGLR
LIGAPSGEFSWFKGYDWTIALCGQCGSHLGWHYEGGSQPQTFFGLIKDRL
AEGPA
Ligand information
Ligand ID9UW
InChIInChI=1S/C3H2N2OS/c6-2-1-4-3(7)5-2/h1H,(H,5,6,7)
InChIKeyKAKLKODZMNCHIC-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.6C1=NC(=S)NC1=O
CACTVS 3.385O=C1NC(=S)N=C1
FormulaC3 H2 N2 O S
Name2-sulfanylideneimidazol-4-one
ChEMBL
DrugBank
ZINC
PDB chain5oha Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5oha Chemical Ligand Space of Cereblon.
Resolution1.55 Å
Binding residue
(original residue number in PDB)		F77 W79 W85 W99 Y101
Binding residue
(residue number reindexed from 1)		F59 W61 W67 W81 Y83
Annotation score1
Binding affinityPDBbind-CN: -logKd/Ki=4.89,Kd=13uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5oha, PDBe:5oha, PDBj:5oha
PDBsum5oha
PubMed31459225
UniProtA4TVL0

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