Structure of PDB 5oh9 Chain A Binding Site BS02

Receptor Information
>5oh9 Chain A (length=106) Species: 55518 (Magnetospirillum gryphiswaldense) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GASIFRCRQCGQTISRRDWLLPMGGDHEHVVFNPAGMIFRVWCFSLAQGL
RLIGAPSGEFSWFKGYDWTIALCGQCGSHLGWHYEGGSQPQTFFGLIKDR
LAEGPA
Ligand information
Ligand ID9UT
InChIInChI=1S/C3H3NO2S/c5-2-1-7-3(6)4-2/h1,7H,(H,4,5,6)
InChIKeyOKCMWAHWBYXJPD-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.385O=C1NC(=O)[SH]=C1
OpenEye OEToolkits 2.0.6C1=SC(=O)NC1=O
FormulaC3 H3 N O2 S
Name1,3-thiazole-2,4-dione
ChEMBL
DrugBank
ZINC
PDB chain5oh9 Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5oh9 Chemical Ligand Space of Cereblon.
Resolution1.65 Å
Binding residue
(original residue number in PDB)		F77 W79 W85 W99 Y101
Binding residue
(residue number reindexed from 1)		F60 W62 W68 W82 Y84
Annotation score1
Binding affinityPDBbind-CN: -logKd/Ki=3.86,Ki=137uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5oh9, PDBe:5oh9, PDBj:5oh9
PDBsum5oh9
PubMed31459225
UniProtA4TVL0

[Back to BioLiP]