Structure of PDB 5n91 Chain A Binding Site BS02
Receptor Information
>5n91 Chain A (length=113) Species:
9606
(Homo sapiens) [
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GSMSEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRV
VGRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDAN
VFASAMMHALEVL
Ligand information
>5n91 Chain G (length=4) Species:
32630
(synthetic construct) [
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PPPP
Receptor-Ligand Complex Structure
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PDB
5n91
Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Resolution
1.49 Å
Binding residue
(original residue number in PDB)
Y38 R47 V58 N61
Binding residue
(residue number reindexed from 1)
Y40 R49 V60 N63
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5n91
,
PDBe:5n91
,
PDBj:5n91
PDBsum
5n91
PubMed
33184177
UniProt
Q8N8S7
|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)
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