Structure of PDB 5n8m Chain A Binding Site BS02

Receptor Information
>5n8m Chain A (length=155) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GGSLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNF
TFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGCNPVGALQELVVQKG
WRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML
LRVHT
Ligand information
>5n8m Chain C (length=21) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guacggaauagauaauuaauu
.....................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5n8m Structural basis of siRNA recognition by TRBP double-stranded RNA binding domains.
ResolutionN/A
Binding residue
(original residue number in PDB)
T30 I32 S33 Q36 A57 K81 K84 Q165 E166 V169 A187 F192 T208 S209 K210
Binding residue
(residue number reindexed from 1)
T18 I20 S21 Q24 A45 K69 K72 Q93 E94 V97 A115 F120 T136 S137 K138
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5n8m, PDBe:5n8m, PDBj:5n8m
PDBsum5n8m
PubMed29449323
UniProtQ15633|TRBP2_HUMAN RISC-loading complex subunit TARBP2 (Gene Name=TARBP2)

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