Structure of PDB 5mjy Chain A Binding Site BS02

Receptor Information
>5mjy Chain A (length=358) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VPRMPMIWLDLKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQ
NAVRVPRDFEGCSVLRKYLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGK
SVAHEDIKYEQACILYNLGALHSMLGAMDKRVSEEGMKVSCTHFQCAAGA
FAYLREHFPQAYSVDMSRQILTLNVNLMLGQAQECLLEKSMLDNRKSFLV
ARISAQVVDYYKEACRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAH
LHMGKQAEEQQKFGERVAYFQSALDKLNEAIKLAKGQPDTVQDALRFTMD
VIGGKYNSAKKDNDFIYHEAVPALDTLQPVKGAPLVKPLPVNPTDPAVTG
PDIFAKLV
Ligand information
>5mjy Chain F (length=20) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ENYFQAEAYNLDKVLDEFEQ
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5mjy Structural Basis for Specific Interaction of TGF beta Signaling Regulators SARA/Endofin with HD-PTP.
Resolution2.25 Å
Binding residue
(original residue number in PDB)		A358 K359
Binding residue
(residue number reindexed from 1)		A355 K356
Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Gene Ontology
Biological Process
GO:0071985 multivesicular body sorting pathway

View graph for
Biological Process
External links
PDB RCSB:5mjy, PDBe:5mjy, PDBj:5mjy
PDBsum5mjy
PubMed28602823
UniProtQ9H3S7|PTN23_HUMAN Tyrosine-protein phosphatase non-receptor type 23 (Gene Name=PTPN23)

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