Structure of PDB 5lj6 Chain A Binding Site BS02

Receptor Information
>5lj6 Chain A (length=600) Species: 714 (Aggregatibacter actinomycetemcomitans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNIIEIKQLNRYFGEGENRVHVLKDISLSIERGDFVAIMGQSGSGKSTLM
NIIGCLDTATGGSSKIDGKETIELTNDQLSDLRSQKFGFIFQRYNLLSSL
TAAENVALPAIYAGMPQSQRLERAKQLLEKLGLGDKWQNKPNQLSGGQQQ
RVSIARALMNGGEIILADQPTGALDSHSGENVMEILRQLHEEGHTIIMVT
HDKHIAASANRIIEIKDGEIISDTQKRQVKSAVSKDQLMEAFRMSVSAIV
AHKMRSLLTMLGIIIGITSVVSVVALGNGSQQKILENIRGIGTNTMTIFK
ISDANTLSKQSYIQSVTPNTSSSGILVVGNKSFTSANLYGIGEQYFDVEG
LKLKQGRLLTEDDVDQSNQVVVLDESAKKAIFANENPLGKTVIFNKRPFR
VIGVVSDQLNLYSPYSTVLNKITGSITVKISDDVNSTVAEKSLTELLKSL
HGKKDFFIMNSDTIKQTIENTTGTMKLLISSIAFISLIVGGIGVMNIMLV
SVTERTKEIGVRMAIGARQINILQQFLIEAVLICLIGGVAGILLSVLIGV
LFNSFITDFSMDFSTASIVTAVLFSTLIGVLFGYMPAKKAAELNPITALA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5lj6 Chain A Residue 702 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5lj6 Structure and mechanotransmission mechanism of the MacB ABC transporter superfamily.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		S47 Q92 D168
Binding residue
(residue number reindexed from 1)		S47 Q92 D168
Annotation score1
Enzymatic activity
Enzyme Commision number 7.6.2.-
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0046677 response to antibiotic
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5lj6, PDBe:5lj6, PDBj:5lj6
PDBsum5lj6
PubMed29109272
UniProtQ2EHL8|MACB_AGGAC Macrolide export ATP-binding/permease protein MacB (Gene Name=macB)

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