Structure of PDB 5lhm Chain A Binding Site BS02

Receptor Information
>5lhm Chain A (length=213) Species: 34 (Myxococcus xanthus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTQSVLQYIRDSSVRDNDILRDLREETSKLPMQIPPEQGQLLSLLVRLIG
ARKTLEVGVFTGYSTLCTALALPADGRVIACDLSEEWVSIARRYWQRAGV
ADRIEVRLGDAHHSLEALVGSEHRGTFDLAFIDADKESYDFYYEHALRLV
RPGGLIILDNTLWSGKVADPSVVGDPETDSLRRINAKLLTDERVDLSMLP
IADGLTLARKRKL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5lhm Chain A Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5lhm Functional and structural characterisation of a bacterial O-methyltransferase and factors determining regioselectivity.
Resolution1.31 Å
Binding residue
(original residue number in PDB)		Q47 D168 A211 G213
Binding residue
(residue number reindexed from 1)		Q38 D159 A202 G204
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) D142 K145 D168 N169
Catalytic site (residue number reindexed from 1) D133 K136 D159 N160
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008171 O-methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0032259 methylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5lhm, PDBe:5lhm, PDBj:5lhm
PDBsum5lhm
PubMed27990630
UniProtQ50859

[Back to BioLiP]