Structure of PDB 5lg7 Chain A Binding Site BS02

Receptor Information
>5lg7 Chain A (length=69) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQRLIT
NKKCPICRVDIEAQLPSES
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5lg7 Chain A Residue 102 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5lg7 A Residue Specific Insight into the Arkadia E3 Ubiquitin Ligase Activity and Conformational Plasticity.
ResolutionN/A
Binding residue
(original residue number in PDB)		C35 M36 H37 C57
Binding residue
(residue number reindexed from 1)		C35 M36 H37 C57
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0061630 ubiquitin protein ligase activity

View graph for
Molecular Function
External links
PDB RCSB:5lg7, PDBe:5lg7, PDBj:5lg7
PDBsum5lg7
PubMed28647409
UniProtQ6ZNA4|RN111_HUMAN E3 ubiquitin-protein ligase Arkadia (Gene Name=RNF111)

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